Ibuprofen: Miracle Drug or Pain in the Gut? Your Complete Guide

Posted on: , Updated on:
On this article you will find

In the realm of pain relief and fever reduction, Ibuprofen has become a household name. As one of the most commonly used over-the-counter drugs, Ibuprofen has garnered a reputation for its effectiveness and accessibility. This nonsteroidal anti-inflammatory drug (NSAID) has proven to be a reliable ally in managing a wide range of conditions, from minor headaches to arthritis-related discomfort.

It’s commonly used as a pain reliever, fever reducer, and anti-inflammatory medication. It is available over-the-counter and in higher strengths with a prescription. Ibuprofen works by inhibiting the production of prostaglandins, substances in the body that play a role in inflammation and pain. It is often used to alleviate symptoms associated with conditions like headaches, menstrual cramps, dental pain, muscle aches, arthritis, and minor injuries.

Mechanism of action of ibuprofen:

Ibuprofen works by inhibiting the production of specific chemicals in the body called prostaglandins. Prostaglandins are substances that play a key role in promoting inflammation, pain, and fever as part of the body’s natural immune response.

Specifically, ibuprofen blocks the action of enzymes known as cyclooxygenases (COX-1 and COX-2) involved in the production of prostaglandins. By inhibiting COX enzymes, ibuprofen decreases the synthesis of prostaglandins, reducing inflammation and its associated symptoms.

COX-1 enzymes are constitutively present in various tissues throughout the body, including the stomach lining and blood vessels, and play a role in normal physiological functions. COX-2 enzymes, on the other hand, are inducible enzymes that are primarily upregulated at sites of inflammation.

By selectively inhibiting COX-2 enzymes, ibuprofen acts to specifically target inflammation while having minimal effects on COX-1 enzymes. This selectivity helps to reduce the risk of adverse gastrointestinal effects that may be associated with non-selective NSAIDs.

As a result of the reduced production of prostaglandins, ibuprofen effectively reduces pain and swelling associated with inflammation and decreases fever by acting on the hypothalamus, the part of the brain that regulates body temperature.
Continue reading

How useful was this post?

Click on a star to rate it!

Average rating 0 / 5. Vote count: 0

No votes so far! Be the first to rate this post.

As you found this post useful...

Follow us on social media!

We are sorry that this post was not useful for you!

Let us improve this post!

Tell us how we can improve this post?

Follow us on Google News

Related Articles

4 Remedies to prevent Hemorrhoids: Ingredients in Kitchen

4 Home Remedies to prevent Hemorrhoids: Ingredients in Your Kitchen

Hemorrhoids can be uncomfortable and even painful. These swollen veins in the rectum and anus can cause itching, pain, and bleeding. While there are actual effective treatments are available, many …

Read the article icon left
Toothaches in Children: 5 Natural Remedies and What to Avoid

Natural Remedies for Toothaches in Children: What Works and What to Avoid

Toothaches in children can be a stressful experience, both for the child and the parent. The pain can interfere with eating, sleeping, and your child’s overall well-being. While it’s always …

Read the article icon left
Scabies Itch

How to Relieve Scabies Itch with Natural Ingredients

Sarcoptes scabiei, commonly known as scabies, is a parasitic mite that causes intense pruritus (itching), rashes, and lesions. Although infestation is not life threatening, scabies is a nuisance disease that is …

Read the article icon left
icon top